Chris Harris helped get Scotland over the line in the Calcutta Cup, as every away nation recorded victories on the opening weekend for the first time in Six Nations history.
Harris came on as a replacement for Huw Jones in the 76th minute at Twickenham, a couple of minutes after Duhan van der Merwe had put the Scots ahead with his stunning individual score.
England made far from the ideal start to Steve Borthwick’s tenure as the England head coach, with the defeat handing Scotland their third successive Calcutta Cup win.
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Elsewhere, Stephen Varney nearly lead Italy to a famous win over France, with the Azzuri taking a 24-22 lead in the 63rd minute, only for Matthieu Jalibert to go over the line for the visitors a few minutes later.
The defending champions would eventually hold onto the win, with Varney replaced for the final four minutes of the match, but Italy rightly received praise for their gun-ho display, with Ange Capuozzo at the heart of their attack.
France will look to improve their discipline as the tournament goes on, having conceded 19 penalties during the game, allowing Tomasso Allan to kick the hosts into contention.
Varney himself had a difficult start to the match, after his box kick was charged down by Thibaud Flament allowing the lock to score the opening try of the contest, but recovered well, making 83 passes – more than anyone else on the field.
Back row Jake Polledri was not included in Italy’s squad in Rome, and Louis Rees-Zammit continues to recover from injury in the Wales camp.
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Wales were beaten comprehensively 34-10 by Ireland at the Principality Stadium in Warren Gatland’s first match as head coach since returning to the job for a second spell in charge.
It was Ireland’s biggest win in Cardiff since 2004, with Caelan Doris, James Ryan, James Lowe and Josh van der Flier all scoring tries, whilst Johnny Sexton kicked two penalties.
Ireland will now host France on Saturday, February 11, whilst Scotland and Wales will face off later that evening.
Varney and his Italy side will travel to London for a tough test against England, with both teams looking for their first win of the campaign.