In the second of the Super-Sunday fixtures in the Premier League, Tottenham head down to the south coast to take on Bournemouth at the Vitality Stadium (4pm kick-off).
Spurs can move into third with a win over Bournemouth and tighten their grip on a Champions League spot.
Since their 4-1 defeat to league-leaders Manchester City in December, they’ve gone 12 matches unbeaten and conceded just six goals.
Mauricio Pochettino’s side come into the game on the back of a 2-0 victory over Huddersfield at Wembley last Saturday as a Heung Min-Son brace gave Spurs all three points.
Last Saturday also saw Bournemouth earn a 1-1 draw at Leicester City.
A Riyad Mahrez penalty denying the cherries all three points with the last kick of the game.
The result saw Eddie Howe’s side stay 11th in the table but can move above Watford and into the top half of the league if they beat Spurs by two clear goals, and Watford lose at Arsenal in the early kick-off.
Bournemouth have lost the last four meetings between the two sides without scoring a single goal.
Tottenham midfielder Eric Dier is a doubt for the game after sustaining an elbow injury in the midweek Champions League clash with Juventus and faces a late assessment.
Defender Toby Alderweireld remains unavailable because of a hamstring problem, while full-back Serge Aurier is back in contention after his European suspension.
Meanwhile, Bournemouth have doubts over wingers Jordon Ibe, Marc Pugh and Ryan Fraser. Pugh has been carrying a calf problem, while Ibe has been side-lined by a hamstring injury and Fraser, who was on the bench against Leicester last weekend, will be monitored on his back issue.
Defoe, fit again following an ankle injury, could start against one of his old clubs, while defender Tyrone Mings continues his rehabilitation from a back problem.
Bournemouth have lost four of their five Premier League meetings with Tottenham, with the exception being a 0-0 draw in this exact fixture last season.
Tottenham’s only defeat against Bournemouth in any competition was in their only non-Premier League meeting with them – a 1-3 loss in the FA Cup in February 1957.
The Cherries haven’t scored in any of their last four Premier League meetings with Spurs, with Matt Ritchie’s strike 49 seconds into their first ever such meeting with them remaining their only goal in this fixture.
Bournemouth have kept just one clean sheet in their last 16 Premier League games, with that shutout coming in a 3-0 win at Stamford Bridge.
However, the Cherries have only lost one of their last 10 Premier League games (W4 D5) – only Tottenham themselves have lost fewer over the last 10 (0).
Spurs are unbeaten in their last 11 Premier League matches, winning the last three without conceding. They last won four in a row while keeping a clean sheet in April 2017.
The reverse fixture in October between the two sides saw Tottenham narrowly beat Bournemouth 1-0 at Wembley.
A Christian Eriksen strike two minutes after half-time was the difference as Spurs recorded their first Premier League victory of the season at the home of English football.
WATCH: Tottenham Hotspur 1-0 Bournemouth – 14th October 2017: English Premier League.